Gender effects on humoral immune responses to smallpox vaccine

An HIV-1 Mini Vaccine Induced Long-lived Cellular and Humoral Immune Responses

Memory formation is the most important aspect of a vaccine which can guarantee long-lasting immunity and protection. The main aim of the present study was to evaluate the memory immune responses after immunization with a mini vaccine. Mice were immunized with human immunodeficiency virus-1 P24-Nef fusion peptide and then cellular and humoral immune responses were evaluated. In order to determin...

Cell-mediated immune responses to smallpox vaccination.

We report that vaccine dilution (1:1 or 1:10) and previous vaccinia virus vaccination status had no significant effect on cell-mediated immune responses (i.e., the immediate vaccinia virus-specific gamma interferon-producing T-cell response measured by enzyme-linked immunospot assay) 1 month after smallpox vaccination (Lancy-Vaxina; Berna Biotech, Switzerland).

Clinical and immune response to undiluted and diluted smallpox vaccine.

QUESTION UNDER STUDY To assess clinical reactions, immune responses and adverse events to undiluted, three- and sixfold diluted Lister strain vaccine stockpiled in Switzerland. METHODS A prospective, triple-blinded, randomised, parallel group clinical trial was performed. RESULTS From 2001 to 2007 104 persons with an indication for vaccinia vaccination were recruited. They had a median age ...

Humoral Immune Response to Mumps (RS-12 strain) Vaccine of Children 1-7 Years Old

Serological responses in humans to the smallpox vaccine LC16m8

In response to potential bioterrorism with smallpox, members of the Japanese Self-Defense Forces were vaccinated with vaccinia virus (VACV) strain LC16m8, an attenuated smallpox vaccine derived from VACV strain Lister. The serological response induced by LC16m8 to four virion-surface proteins and the intracellular mature virus (IMV) and extracellular enveloped virus (EEV) was investigated. LC16...